Apolipoprotein A-IGiessen (Pro143Arg). A mutant that is defective in activating lecithin:cholesterol acyltransferase
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چکیده
منابع مشابه
Characterization of a temperature-sensitive mutant of Salmonella typhimurium defective in apolipoprotein N-acyltransferase.
On screening 440 temperature-sensitive (ts) mutants of Salmonella typhimurium, a mutant strain SE5312 which accumulated apolipoprotein (ALP) at 42 degrees C was identified. In vitro assay of apolipoprotein N-acyltransferase activity indicated that the mutant cell envelope contained reduced activity as compared to the wild-type strain. Transduction with a Mud-P22 mapping set placed the ts mutati...
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The major protein of high density llpoproteln (HDL), apolipoprotein (apo) A-l, is the major activator of the plasma enzyme lecithin:cholesterol acyltransferase (LCAT). A consensus amlno acid sequence has been defined for the eight, 22-resldue long, tandem amphlpathic helical repeats located in the carboxy-terminal region of apo A-l. A series of 22 and 44mer synthetic peptide analogues of the co...
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The major protein of high density lipoprotein (HDL), apolipoprotein (apo) A-I, is the major activator of the plasma enzyme lecithin:cholesterol acyltransferase (LCAT). A consensus amino acid sequence has been defined for the eight, 22-residue long, tandem amphipathic helical repeats located in the carboxy-terminal region of apo A-I. A series of 22 and 44mer synthetic peptide analogues of the co...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1984
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1984.tb08467.x